(Z)-2-(((1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)(HYDROXY)METHYLENE)AMINO)ACETIC ACID
FG-2216
CAS: 223387-75-5
Molecular Formula: C12H9ClN2O4
(Z)-2-(((1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)(HYDROXY)METHYLENE)AMINO)ACETIC ACID - Names and Identifiers
(Z)-2-(((1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)(HYDROXY)METHYLENE)AMINO)ACETIC ACID - Physico-chemical Properties
| Molecular Formula | C12H9ClN2O4 |
| Molar Mass | 280.66 |
| Density | 1.571±0.06 g/cm3(Predicted) |
| Boling Point | 670.6±55.0 °C(Predicted) |
| Solubility | DMSO: ≥ 31 mg/mL |
| Appearance | powder |
| Color | white to beige |
| pKa | 3.20±0.10(Predicted) |
| Storage Condition | -20°C |
| In vitro study | In male rhesus monkeys, FG-2216 (60 mg/kg, p.o.) induced significant and reversible Epo induction and a small increase in HbF expression. |
(Z)-2-(((1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)(HYDROXY)METHYLENE)AMINO)ACETIC ACID - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.563 ml | 17.815 ml | 35.63 ml |
| 5 mM | 0.713 ml | 3.563 ml | 7.126 ml |
| 10 mM | 0.356 ml | 1.781 ml | 3.563 ml |
| 5 mM | 0.071 ml | 0.356 ml | 0.713 ml |
Last Update：2024-01-02 23:10:35
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View History
(Z)-2-(((1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)(HYDROXY)METHYLENE)AMINO)ACETIC ACID
4-CHLORO-2-(3-CHLOROPHENYL)-5-[(2-HYDROXYETHYL)AMINO]-3(2H)-PYRIDAZINONE
isodecylphosphite
1-[2-(吗啉-4-基)乙基]-1H-吡唑-4-羧酸盐酸
1-环丙基-1H-吡唑并[3,4-d]嘧啶-6-甲酸
2-{7-[2-(dimethylamino)ethyl]-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl}ethyl 3,4,5-trimethoxybenzoate
(S)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine hydrochloride
N-[3-TRIETHOXYSILYLPROPYL]-2,4 DINITROPHENYLAMINE
4-hydroxy-4-(5-pyrimidin-2-yl-2-pyridyl)cyclohexanone
Boc-Val-Pro-Arg-AMC hydrochloride salt
4-CHLORO-2-(3-CHLOROPHENYL)-5-[(2-HYDROXYETHYL)AMINO]-3(2H)-PYRIDAZINONE
isodecylphosphite
1-[2-(吗啉-4-基)乙基]-1H-吡唑-4-羧酸盐酸
1-环丙基-1H-吡唑并[3,4-d]嘧啶-6-甲酸
2-{7-[2-(dimethylamino)ethyl]-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl}ethyl 3,4,5-trimethoxybenzoate
(S)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine hydrochloride
N-[3-TRIETHOXYSILYLPROPYL]-2,4 DINITROPHENYLAMINE
4-hydroxy-4-(5-pyrimidin-2-yl-2-pyridyl)cyclohexanone
Boc-Val-Pro-Arg-AMC hydrochloride salt